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Thalidomide-NH-C6-NH2 hydrochloride
CAS No. 2375194-37-7
Thalidomide-NH-C6-NH2 hydrochloride( Pomalidomide-C6-NH2 hydrochloride )
Catalog No. M28256 CAS No. 2375194-37-7
Pomalidomide-C6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based CRBN ligand and linker used in PROTAC technology.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 61 | In Stock |
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| 5MG | 88 | In Stock |
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| 10MG | 128 | In Stock |
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| 25MG | 230 | In Stock |
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| 50MG | 347 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameThalidomide-NH-C6-NH2 hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionPomalidomide-C6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based CRBN ligand and linker used in PROTAC technology.
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DescriptionPomalidomide-C6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based CRBN ligand and linker used in PROTAC technology.
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In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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In Vivo——
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SynonymsPomalidomide-C6-NH2 hydrochloride
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PathwayOthers
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TargetOther Targets
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RecptorATPase|Calcium Channel|PAFR|Potassium Channel
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Research Area——
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Indication——
Chemical Information
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CAS Number2375194-37-7
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Formula Weight408.88
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Molecular FormulaC19H25ClN4O4
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Purity>98% (HPLC)
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Solubility——
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SMILESCl.NCCCCCCNc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Teng CM, et al. Inhibition of thrombin- and collagen-induced phosphoinositides breakdown in rabbit platelets by a PAF antagonist--denudatin B, an isomer of kadsurenone. Thromb Res. 1990 Jul 1;59(1):121-30.
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